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2A0K

Crystal structure of Nucleoside 2-deoxyribosyltransferase from Trypanosoma brucei at 1.8 A resolution

Summary for 2A0K
Entry DOI10.2210/pdb2a0k/pdb
DescriptorNucleoside 2-deoxyribosyltransferase, SULFATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywordssgpp, structural genomics, psi, protein structure initiative, nucleoside 2-deoxyribosyltransferase, structural genomics of pathogenic protozoa consortium, transferase
Biological sourceTrypanosoma brucei
Total number of polymer chains2
Total formula weight37704.45
Authors
Bosch, J.,Robien, M.A.,Hol, W.G.J.,Structural Genomics of Pathogenic Protozoa Consortium (SGPP) (deposition date: 2005-06-16, release date: 2005-07-26, Last modification date: 2021-10-20)
Primary citationBosch, J.,Robien, M.A.,Mehlin, C.,Boni, E.,Riechers, A.,Buckner, F.S.,Van Voorhis, W.C.,Myler, P.J.,Worthey, E.A.,DeTitta, G.,Luft, J.R.,Lauricella, A.,Gulde, S.,Anderson, L.A.,Kalyuzhniy, O.,Neely, H.M.,Ross, J.,Earnest, T.N.,Soltis, M.,Schoenfeld, L.,Zucker, F.,Merritt, E.A.,Fan, E.,Verlinde, C.L.,Hol, W.G.J.
Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.
J.Med.Chem., 49:5939-5946, 2006
Cited by
PubMed: 17004709
DOI: 10.1021/jm060429m
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

218500

数据于2024-04-17公开中

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