2A0K

Crystal structure of Nucleoside 2-deoxyribosyltransferase from Trypanosoma brucei at 1.8 A resolution

2A0K の概要

• エントリーDOI: 10.2210/pdb2a0k/pdb
• 分子名称: Nucleoside 2-deoxyribosyltransferase, SULFATE ION, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: sgpp, structural genomics, psi, protein structure initiative, nucleoside 2-deoxyribosyltransferase, structural genomics of pathogenic protozoa consortium, transferase
• 由来する生物種: Trypanosoma brucei
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 37704.45

構造登録者

Bosch, J.,Robien, M.A.,Hol, W.G.J.,Structural Genomics of Pathogenic Protozoa Consortium (SGPP) (登録日: 2005-06-16, 公開日: 2005-07-26, 最終更新日: 2021-10-20)

• 主引用文献: Bosch, J.,Robien, M.A.,Mehlin, C.,Boni, E.,Riechers, A.,Buckner, F.S.,Van Voorhis, W.C.,Myler, P.J.,Worthey, E.A.,DeTitta, G.,Luft, J.R.,Lauricella, A.,Gulde, S.,Anderson, L.A.,Kalyuzhniy, O.,Neely, H.M.,Ross, J.,Earnest, T.N.,Soltis, M.,Schoenfeld, L.,Zucker, F.,Merritt, E.A.,Fan, E.,Verlinde, C.L.,Hol, W.G.J.; Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.; J.Med.Chem., 49:5939-5946, 2006; PubMed: 17004709; DOI: 10.1021/jm060429m

実験手法

X-RAY DIFFRACTION (1.8 Å)