2A05
The cysteine-rich secretory protein domain of Tpx-1 is related to ion channel toxins and regulates Ryanodine receptor Ca2+ signaling
Summary for 2A05
| Entry DOI | 10.2210/pdb2a05/pdb |
| NMR Information | BMRB: 6740 |
| Descriptor | Cysteine-rich secretory protein-2 (1 entity in total) |
| Functional Keywords | 3 alpha helices, 5 disulphide bonds, 2 domains, signaling protein |
| Biological source | Mus musculus (house mouse) |
| Cellular location | Secreted (Probable): P16563 |
| Total number of polymer chains | 1 |
| Total formula weight | 6121.93 |
| Authors | Gibbs, G.M.,Scanlon, M.J.,Swarbrick, J.,Curtis, S.,Dulhunty, A.F.,O'Bryan, M.K. (deposition date: 2005-06-15, release date: 2006-01-17, Last modification date: 2022-03-09) |
| Primary citation | Gibbs, G.M.,Scanlon, M.J.,Swarbrick, J.,Curtis, S.,Gallant, E.,Dulhunty, A.F.,O'Bryan, M.K. The cysteine-rich secretory protein domain of Tpx-1 is related to ion channel toxins and regulates ryanodine receptor Ca2+ signaling. J.Biol.Chem., 281:4156-4163, 2006 Cited by PubMed: 16339766DOI: 10.1074/jbc.M506849200 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
Download full validation report
