2ZWL

Human factor viia-tissue factor complexed with highly selective peptide inhibitor

Summary for 2ZWL

• Entry DOI: 10.2210/pdb2zwl/pdb
• Descriptor: Factor VII light chain, Factor VII heavy chain, Tissue factor, ... (8 entities in total)
• Functional Keywords: serine protease, alternative splicing, blood coagulation, calcium, cleavage on pair of basic residues, disease mutation, egf-like domain, gamma-carboxyglutamic acid, glycoprotein, hydrolase, hydroxylation, pharmaceutical, polymorphism, protease, zymogen, lipoprotein, membrane, palmitate, transmembrane, hydrolase-blood clotting complex, secreted, hydrolase/blood clotting
• Biological source: Homo sapiens (Human); More
• Cellular location: Secreted: P08709 P08709; Membrane; Single-pass type I membrane protein: P13726
• Total number of polymer chains: 3
• Total formula weight: 71578.38

Authors

Kadono, S.,Sakamoto, A.,Kikuchi, Y.,Oh-Eda, M.,Yabuta, N.,Koga, T.,Hattori, K.,Shiraishi, T.,Haramura, M.,Sato, H.,Ohta, M.,Kozono, T. (deposition date: 2008-12-16, release date: 2009-01-20, Last modification date: 2023-11-15)

• Primary citation: Kadono, S.,Sakamoto, A.,Kikuchi, Y.,Oh-Eda, M.,Yabuta, N.,Koga, T.,Hattori, K.,Shiraishi, T.,Haramura, M.,Sato, H.,Ohta, M.,Kozono, T.; Human factor viia-tissue factor complexed with highly selective peptide inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)