2Z3D
A Mechanistic view of Enzyme Inhibition and Peptide Hydrolysis in the Active Site of the SARS-CoV 3C-Like peptidase
Summary for 2Z3D
Entry DOI | 10.2210/pdb2z3d/pdb |
Related | 2Z3C |
Related PRD ID | PRD_000235 |
Descriptor | Replicase polyprotein 1ab (pp1ab), Inhibitor, GLYCEROL, ... (4 entities in total) |
Functional Keywords | beta barrels, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | SARS coronavirus (SARS-CoV) More |
Total number of polymer chains | 2 |
Total formula weight | 34422.31 |
Authors | |
Primary citation | Yin, J.,Niu, C.,Cherney, M.M.,Zhang, J.,Huitema, C.,Eltis, L.D.,Vederas, J.C.,James, M.N. A mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the SARS-CoV 3C-like peptidase J.Mol.Biol., 371:1060-1074, 2007 Cited by PubMed: 17599357DOI: 10.1016/j.jmb.2007.06.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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