2YGQ

WIF domain-epidermal growth factor (EGF)-like domains 1-3 of human Wnt inhibitory factor 1 in complex with 1,2- dipalmitoylphosphatidylcholine

Summary for 2YGQ

• Entry DOI: 10.2210/pdb2ygq/pdb
• Related: 2YGN 2YGO 2YGP
• Related PRD ID: PRD_900013
• Descriptor: WNT INHIBITORY FACTOR 1, 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, ... (5 entities in total)
• Functional Keywords: signaling protein, wnt signaling pathway, wnt antagonist, morphogen, cancer, glycosaminoglycan
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Secreted: Q9Y5W5
• Total number of polymer chains: 1
• Total formula weight: 37725.04

Authors

Malinauskas, T.,Aricescu, A.R.,Lu, W.,Siebold, C.,Jones, E.Y. (deposition date: 2011-04-19, release date: 2011-07-13, Last modification date: 2020-07-29)

• Primary citation: Malinauskas, T.,Aricescu, A.R.,Lu, W.,Siebold, C.,Jones, E.Y.; Modular Mechanism of Wnt Signaling Inhibition by Wnt Inhibitory Factor 1; Nat.Struct.Mol.Biol., 18:886-, 2011; PubMed: 21743455; DOI: 10.1038/NSMB.2081

Experimental method

X-RAY DIFFRACTION (3.951 Å)