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2XS0

Linear binding motifs for JNK and for calcineurin antagonistically control the nuclear shuttling of NFAT4

Summary for 2XS0
Entry DOI10.2210/pdb2xs0/pdb
Related1UKH 1UKI 2GMX 2H96 2XRW
DescriptorMITOGEN-ACTIVATED PROTEIN KINASE 8, NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
Functional Keywordstranscription, transferase, mapk signaling pathways, linear binding motifs
Biological sourceHOMO SAPIENS (HUMAN)
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Cellular locationCytoplasm: P45983 Q12968
Total number of polymer chains2
Total formula weight46453.23
Authors
Barkai, T.,Toeoroe, I.,Garai, A.,Remenyi, A. (deposition date: 2010-09-24, release date: 2011-09-28, Last modification date: 2023-12-20)
Primary citationGarai, A.,Zeke, A.,Gogl, G.,Toro, I.,Fordos, F.,Blankenburg, H.,Barkai, T.,Varga, J.,Alexa, A.,Emig, D.,Albrecht, M.,Remenyi, A.
Specificity of Linear Motifs that Bind to a Common Mitogen-Activated Protein Kinase Docking Groove.
Sci. Signal, 5:74-, 2012
Cited by
PubMed: 23047924
DOI: 10.1126/SCISIGNAL.2003004
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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