2XDE
Crystal structure of the complex of PF-3450074 with an engineered HIV capsid N terminal domain
Summary for 2XDE
Entry DOI | 10.2210/pdb2xde/pdb |
Descriptor | GAG POLYPROTEIN, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE (3 entities in total) |
Functional Keywords | aids, viral protein |
Biological source | HUMAN IMMUNODEFICIENCY VIRUS 1 |
Total number of polymer chains | 2 |
Total formula weight | 33286.03 |
Authors | Brown, D.G.,Irving, S.L.,Anderson, M.,Bazin, R. (deposition date: 2010-04-30, release date: 2010-12-22, Last modification date: 2024-05-01) |
Primary citation | Blair, W.S.,Pickford, C.,Irving, S.L.,Brown, D.G.,Anderson, M.,Bazin, R.,Cao, J.,Ciaramella, G.,Isaacson, J.,Jackson, L.,Hunt, R.,Kjerrstrom, A.,Nieman, J.,Patick, A.K.,Perros, M.,Scott, A.D.,Whitby, K.,Wu, H.,Butler, S.L. HIV Capsid is a Tractable Target for Small Molecule Therapeutic Intervention. Plos Pathog., 6:E1220-, 2010 Cited by PubMed: 21170360DOI: 10.1371/JOURNAL.PPAT.1001220 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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