2XC3

X-ray structure of Mycobacterium tuberculosis cyp125 bound to the reverse type I inhibitor

Summary for 2XC3

• Entry DOI: 10.2210/pdb2xc3/pdb
• Related: 2X5L 2X5W
• Descriptor: PUTATIVE CYTOCHROME P450 125, PROTOPORPHYRIN IX CONTAINING FE, NALPHA-[(TRANS-4-METHYLCYCLOHEXYL)CARBONYL]-N-PYRIDIN-4-YL-D-TRYPTOPHANAMIDE, ... (4 entities in total)
• Functional Keywords: oxidoreductase, metal-binding
• Biological source: MYCOBACTERIUM TUBERCULOSIS
• Total number of polymer chains: 1
• Total formula weight: 48614.50

Authors

Ouellet, H.,Kells, P.M.,Ortiz de Montellano, P.R.,Podust, L.M. (deposition date: 2010-04-16, release date: 2010-11-10, Last modification date: 2023-12-20)

• Primary citation: Ouellet, H.,Kells, P.M.,Ortiz de Montellano, P.R.,Podust, L.M.; Reverse Type I Inhibitor of Mycobacteriumtuberculosis Cyp125A1.; Bioorg.Med.Chem.Lett., 21:332-, 2011; PubMed: 21109436; DOI: 10.1016/J.BMCL.2010.11.007

Experimental method

X-RAY DIFFRACTION (1.5 Å)