2WQP
Crystal structure of sialic acid synthase NeuB-inhibitor complex
Summary for 2WQP
Entry DOI | 10.2210/pdb2wqp/pdb |
Descriptor | POLYSIALIC ACID CAPSULE BIOSYNTHESIS PROTEIN SIAC, 5-(ACETYLAMINO)-3,5-DIDEOXY-2-O-PHOSPHONO-D-ERYTHRO-L-MANNO-NONONIC ACID, MANGANESE (II) ION, ... (7 entities in total) |
Functional Keywords | neub, inhibitor, tim barrel, sialic acid synthase, transferase |
Biological source | NEISSERIA MENINGITIDIS |
Total number of polymer chains | 1 |
Total formula weight | 39768.33 |
Authors | Liu, F.,Lee, H.J.,Strynadka, N.C.J.,Tanner, M.E. (deposition date: 2009-08-25, release date: 2009-09-15, Last modification date: 2011-10-12) |
Primary citation | Liu, F.,Lee, H.J.,Strynadka, N.C.J.,Tanner, M.E. The Inhibition of Neisseria Meningitidis Sialic Acid Synthase by a Tetrahedral Intermediate Analog. Biochemistry, 48:9194-, 2009 Cited by PubMed: 19719325DOI: 10.1021/BI9012758 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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