2WNF
Crystal Structure of a Mammalian Sialyltransferase in complex with Gal-beta-1-3GalNAc-ortho-nitrophenol
Summary for 2WNF
Entry DOI | 10.2210/pdb2wnf/pdb |
Related | 2WML 2WNB |
Related PRD ID | PRD_900084 |
Descriptor | CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose, HYDROXY(2-HYDROXYPHENYL)OXOAMMONIUM, ... (4 entities in total) |
Functional Keywords | glycosyltransferase, disulfide bond, golgi apparatus, sialyltransferase, glycoprotein, signal-anchor, transmembrane, membrane, secreted, transferase, sialic acid |
Biological source | SUS SCROFA (PIG) |
Cellular location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: Q02745 |
Total number of polymer chains | 1 |
Total formula weight | 35271.41 |
Authors | Rao, F.V.,Rich, J.R.,Raikic, B.,Wakarchuk, W.W.,Withers, S.G.,Strynadka, N.C.J. (deposition date: 2009-07-09, release date: 2009-10-13, Last modification date: 2023-12-13) |
Primary citation | Rao, F.V.,Rich, J.R.,Rakic, B.,Buddai, S.,Schwartz, M.F.,Johnson, K.,Bowe, C.,Wakarchuk, W.W.,Defrees, S.,Withers, S.G.,Strynadka, N.C.J. Structural Insight Into Mammalian Sialyltransferases. Nat.Struct.Mol.Biol., 16:1186-, 2009 Cited by PubMed: 19820709DOI: 10.1038/NSMB.1685 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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