2WMK
Crystal structure of the catalytic module of a family 98 glycoside hydrolase from Streptococcus pneumoniae SP3-BS71 (Sp3GH98) in complex with the A-LewisY pentasaccharide blood group antigen.
Summary for 2WMK
Entry DOI | 10.2210/pdb2wmk/pdb |
Related | 2WMI 2WMJ |
Related PRD ID | PRD_900127 |
Descriptor | FUCOLECTIN-RELATED PROTEIN, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | blood group, antigen, fucose utilization, hydrolase |
Biological source | STREPTOCOCCUS PNEUMONIAE |
Total number of polymer chains | 2 |
Total formula weight | 141432.29 |
Authors | Higgins, M.A.,Whitworth, G.E.,El Warry, N.,Randriantsoa, M.,Samain, E.,Burke, R.D.,Vocadlo, D.J.,Boraston, A.B. (deposition date: 2009-06-30, release date: 2009-07-14, Last modification date: 2024-05-08) |
Primary citation | Higgins, M.A.,Whitworth, G.E.,El Warry, N.,Randriantsoa, M.,Samain, E.,Burke, R.D.,Vocadlo, D.J.,Boraston, A.B. Differential Recognition and Hydrolysis of Host Carbohydrate-Antigens by Streptococcus Pneumoniae Family 98 Glycoside Hydrolases. J.Biol.Chem., 284:26161-, 2009 Cited by PubMed: 19608744DOI: 10.1074/JBC.M109.024067 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report