2WK0
Crystal structure of the class A beta-lactamase BS3 inhibited by 6- beta-iodopenicillanate.
Summary for 2WK0
Entry DOI | 10.2210/pdb2wk0/pdb |
Related | 1W7F |
Descriptor | BETA-LACTAMASE, (3S)-2,2-dimethyl-3,4-dihydro-2H-1,4-thiazine-3,6-dicarboxylic acid, CHLORIDE ION, ... (7 entities in total) |
Functional Keywords | hydrolase, beta- lactamase, iodopenicillanate, antibiotic resistance, bacillus licheniformis |
Biological source | BACILLUS LICHENIFORMIS |
Total number of polymer chains | 2 |
Total formula weight | 60004.46 |
Authors | Sauvage, E.,Zervosen, A.,Dive, G.,Herman, R.,Kerff, F.,Amoroso, A.,Fonze, E.,Pratt, R.F.,Luxen, A.,Charlier, P. (deposition date: 2009-06-03, release date: 2009-12-01, Last modification date: 2023-12-13) |
Primary citation | Sauvage, E.,Zervosen, A.,Dive, G.,Herman, R.,Amoroso, A.,Joris, B.,Fonze, E.,Pratt, R.F.,Luxen, A.,Charlier, P.,Kerff, F. Structural Basis of the Inhibition of Class a Beta-Lactamases and Penicillin-Binding Proteins by 6-Beta-Iodopenicillanate. J.Am.Chem.Soc., 131:15262-, 2009 Cited by PubMed: 19919161DOI: 10.1021/JA9051526 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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