2WF7

Structure of Beta-Phosphoglucomutase inhibited with Glucose-6- phosphonate and Aluminium tetrafluoride

Summary for 2WF7

Entry DOI	10.2210/pdb2wf7/pdb
Related	1LVH 1O03 1O08 1Z4N 1Z4O 1ZOL 2WF5 2WF6 2WF8 2WF9 2WFA 4C4R
Descriptor	BETA-PHOSPHOGLUCOMUTASE, TETRAFLUOROALUMINATE ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	transition state analogue, haloacid dehalogenase superfamily, isomerase, phosphotransferase
Biological source	LACTOCOCCUS LACTIS
Cellular location	Cytoplasm (Potential): P71447
Total number of polymer chains	1
Total formula weight	24649.34
Authors	Bowler, M.W.,Baxter, N.J.,Webster, C.E.,Pollard, S.,Alizadeh, T.,Hounslow, A.M.,Cliff, M.J.,Bermel, W.,Williams, N.H.,Hollfelder, F.,Blackburn, G.M.,Waltho, J.P. (deposition date: 2009-04-03, release date: 2010-05-19, Last modification date: 2020-07-29)
Primary citation	Jin, Y.,Bhattasali, D.,Pellegrini, E.,Forget, S.M.,Baxter, N.J.,Cliff, M.J.,Bowler, M.W.,Jakeman, D.L.,Blackburn, G.M.,Waltho, J.P. Alpha-Fluorophosphonates Reveal How a Phosphomutase Conserves Transition State Conformation Over Hexose Recognition in its Two-Step Reaction. Proc.Natl.Acad.Sci.USA, 111:12384-, 2014 Cited by PubMed: 25104750 DOI: 10.1073/PNAS.1402850111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.05 Å)

Structure validation