2VZ0
Pteridine Reductase 1 (PTR1) from Trypanosoma Brucei in complex with NADP and DDD00066641
Summary for 2VZ0
Entry DOI | 10.2210/pdb2vz0/pdb |
Related | 2C7V |
Descriptor | PTERIDINE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 6-(4-methylphenyl)quinazoline-2,4-diamine, ... (4 entities in total) |
Functional Keywords | oxidoreductase, short-chain dehydrogenase/reductase, trypanosomatids, pteridine reductase |
Biological source | TRYPANOSOMA BRUCEI BRUCEI |
Total number of polymer chains | 4 |
Total formula weight | 117968.58 |
Authors | Robinson, D.A.,Thompson, S.,Sienkiewicz, N.,Fairlamb, A.H. (deposition date: 2008-07-29, release date: 2009-09-22, Last modification date: 2023-12-13) |
Primary citation | Shanks, E.J.,Ong, H.B.,Robinson, D.A.,Thompson, S.,Sienkiewicz, N.,Fairlamb, A.H.,Frearson, J.A. Development and Validation of a Cytochrome C Coupled Assay for Pteridine Reductase 1 and Dihydrofolate Reductase. Anal.Biochem., 396:194-, 2010 Cited by PubMed: 19748480DOI: 10.1016/J.AB.2009.09.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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