2VS0

Structural analysis of homodimeric staphylococcal aureus virulence factor EsxA

Summary for 2VS0

Entry DOI	10.2210/pdb2vs0/pdb
Related	2VRZ
Descriptor	VIRULENCE FACTOR ESXA, ZINC ION, CACODYLATE ION, ... (4 entities in total)
Functional Keywords	secreted, virulence, four helical bundle, cell invasion
Biological source	STAPHYLOCOCCUS AUREUS
Cellular location	Secreted (By similarity): Q99WU4
Total number of polymer chains	2
Total formula weight	22835.77
Authors	Sundaramoorthy, R.,Fyfe, P.K.,Hunter, W.N. (deposition date: 2008-04-17, release date: 2008-08-26, Last modification date: 2011-07-13)
Primary citation	Sundaramoorthy, R.,Fyfe, P.K.,Hunter, W.N. Structure of Staphylococcus Aureus Esxa Suggests a Contribution to Virulence by Action as a Transport Chaperone and/or Adaptor Protein. J.Mol.Biol., 383:603-, 2008 Cited by PubMed: 18773907 DOI: 10.1016/J.JMB.2008.08.047 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation