2VL3
Oxidized and reduced forms of human peroxiredoxin 5
Summary for 2VL3
Entry DOI | 10.2210/pdb2vl3/pdb |
Related | 1H4O 1HD2 1OC3 1URM 2VL2 |
Descriptor | PEROXIREDOXIN-5 (2 entities in total) |
Functional Keywords | thioredoxin peroxidase, alternative initiation, antioxidant enzyme, redox-active center, cytoplasm, peroxidase, peroxisome, antioxidant, polymorphism, mitochondrion, peroxiredoxin, oxidoreductase, transit peptide, thioredoxin fold |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 3 |
Total formula weight | 54581.55 |
Authors | Smeets, A.,Declercq, J.P. (deposition date: 2008-01-08, release date: 2008-08-26, Last modification date: 2023-12-13) |
Primary citation | Smeets, A.,Marchand, C.,Linard, D.,Knoops, B.,Declercq, J.P. The Crystal Structures of Oxidized Forms of Human Peroxiredoxin 5 with an Intramolecular Disulfide Bond Confirm the Proposed Enzymatic Mechanism for Atypical 2-Cys Peroxiredoxins. Arch.Biochem.Biophys., 477:98-, 2008 Cited by PubMed: 18489898DOI: 10.1016/J.ABB.2008.04.036 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.83 Å) |
Structure validation
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