2VCO

Crystal structure of the fimbrial adhesin FimH in complex with its high-mannose epitope

Summary for 2VCO

Entry DOI	10.2210/pdb2vco/pdb
Related	1KIU 1KLF 1QUN 1TR7 1UWF 1ZE3
Descriptor	PROTEIN FIMH, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NICKEL (II) ION, ... (5 entities in total)
Functional Keywords	pili, glycan, mannose, cell adhesion
Biological source	ESCHERICHIA COLI
Total number of polymer chains	2
Total formula weight	35868.75
Authors	Wellens, A.,Garofalo, C.,Nguyen, H.,Wyns, L.,De Greve, H.,Hultgren, S.J.,Bouckaert, J. (deposition date: 2007-09-26, release date: 2008-05-13, Last modification date: 2023-12-13)
Primary citation	Wellens, A.,Garofalo, C.,Nguyen, H.,Van Gerven, N.,Slattegard, R.,Hernalsteens, J.P.,Wyns, L.,Oscarson, S.,De Greve, H.,Hultgren, S.J.,Bouckaert, J. Intervening with Urinary Tract Infections Using Anti-Adhesives Based on the Crystal Structure of the Fimh-Oligomannose-3 Complex. Plos One, 3:E2040-, 2008 Cited by PubMed: 18446213 DOI: 10.1371/JOURNAL.PONE.0002040 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation