2V6H

Crystal structure of the C1 domain of cardiac myosin binding protein-C

Summary for 2V6H

• Entry DOI: 10.2210/pdb2v6h/pdb
• Related: 1GXE 1PD6
• Descriptor: MYOSIN-BINDING PROTEIN C, CARDIAC-TYPE (2 entities in total)
• Functional Keywords: cell adhesion, phosphorylation, mybp-c c1 domain, disease mutation, muscle regulation, igi domain structure, muscle protein, cardiomyopathy, thick filament, immunoglobulin domain, hypertropic cardiomyopathy, polymorphism, actin-binding
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 12049.61

Authors

Govata, L.,Carpenter, L.,Da Fonseca, P.C.A.,Helliwell, J.R.,Rizkallah, P.J.,Flashman, E.,Chayen, N.E.,Redwood, C.,Squire, J.M. (deposition date: 2007-07-18, release date: 2008-07-22, Last modification date: 2019-05-08)

• Primary citation: Govada, L.,Carpenter, L.,da Fonseca, P.C.,Helliwell, J.R.,Rizkallah, P.,Flashman, E.,Chayen, N.E.,Redwood, C.,Squire, J.M.; Crystal structure of the C1 domain of cardiac myosin binding protein-C: implications for hypertrophic cardiomyopathy.; J. Mol. Biol., 378:387-397, 2008; PubMed: 18374358; DOI: 10.1016/j.jmb.2008.02.044

Experimental method

X-RAY DIFFRACTION (1.55 Å)