2UYX

metallo-beta-lactamase (1BC2) single point mutant D120S

Summary for 2UYX

Entry DOI	10.2210/pdb2uyx/pdb
Related	1BC2 1BMC 1BVT 1DXK 1MQO 2BC2 2BFK 2BFL 2BFZ 2BG2 2BG6 2BG7 2BG8 2BGA 3BC2
Descriptor	BETA-LACTAMASE II, GLYCEROL, ZINC ION, ... (4 entities in total)
Functional Keywords	hydrolase, penicillinase, metal-binding, antibiotic resistance, metallo beta- lactamase
Biological source	BACILLUS CEREUS
Total number of polymer chains	1
Total formula weight	25537.80
Authors	Larrull, L.I.,Fabiane, S.M.,Kowalski, J.M.,Bennett, B.,Sutton, B.J.,Vila, A.J. (deposition date: 2007-04-20, release date: 2007-05-08, Last modification date: 2023-12-13)
Primary citation	Llarrull, L.I.,Fabiane, S.M.,Kowalski, J.M.,Bennett, B.,Sutton, B.J.,Vila, A.J. Asp-120 locates Zn2 for optimal metallo-beta-lactamase activity. J. Biol. Chem., 282:18276-18285, 2007 Cited by PubMed: 17426028 DOI: 10.1074/jbc.M700742200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation