2RUK
Solution structure of the complex between p53 transactivation domain 2 and TFIIH p62 PH domain
Summary for 2RUK
Entry DOI | 10.2210/pdb2ruk/pdb |
NMR Information | BMRB: 11578 |
Descriptor | Cellular tumor antigen p53, General transcription factor IIH subunit 1 (2 entities in total) |
Functional Keywords | antitumor protein, general transcription factor, ph domain, transcription |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637 Nucleus: P32780 |
Total number of polymer chains | 2 |
Total formula weight | 15175.05 |
Authors | Okuda, M.,Nishimura, Y. (deposition date: 2014-09-24, release date: 2014-10-15, Last modification date: 2022-08-24) |
Primary citation | Okuda, M.,Nishimura, Y. Extended string binding mode of the phosphorylated transactivation domain of tumor suppressor p53. J.Am.Chem.Soc., 136:14143-14152, 2014 Cited by PubMed: 25216154DOI: 10.1021/ja506351f PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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