2RSE

NMR structure of FKBP12-mTOR FRB domain-rapamycin complex structure determined based on PCS

Summary for 2RSE

• Entry DOI: 10.2210/pdb2rse/pdb
• NMR Information: BMRB: 11471
• Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1A, Serine/threonine-protein kinase mTOR, TERBIUM(III) ION (3 entities in total)
• Functional Keywords: fkbp12, rapamycin, fk506, lanthanide, pcs, isomerase-transferase complex, isomerase/transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P62942; Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P42345
• Total number of polymer chains: 2
• Total formula weight: 23486.29

Authors

Kobashigawa, Y.,Ushio, M.,Saio, T.,Inagaki, F. (deposition date: 2012-01-25, release date: 2012-05-30, Last modification date: 2023-06-14)

• Primary citation: Kobashigawa, Y.,Saio, T.,Ushio, M.,Sekiguchi, M.,Yokochi, M.,Ogura, K.,Inagaki, F.; Convenient method for resolving degeneracies due to symmetry of the magnetic susceptibility tensor and its application to pseudo contact shift-based protein-protein complex structure determination.; J.Biomol.Nmr, 53:53-63, 2012; PubMed: 22487935; DOI: 10.1007/s10858-012-9623-8

Experimental method

SOLUTION NMR