2RSE

NMR structure of FKBP12-mTOR FRB domain-rapamycin complex structure determined based on PCS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Peptidyl-prolyl cis-trans isomerase FKBP1A	polymer	107	11836.5	1	UniProt (P62942) Pfam (PF00254) In PDB	Homo sapiens (human)	PPIase FKBP1A, 12 kDa FK506-binding protein, 12 kDa FKBP, FKBP-12, FK506-binding protein 1A, FKBP-1A, Immunophilin FKBP12, Rotamase
2	B	Serine/threonine-protein kinase mTOR	polymer	94	11331.9	1	UniProt (P42345) Pfam (PF08771) In PDB	Homo sapiens (human)	FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, mTOR, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapamycin target protein 1
3	A	TERBIUM(III) ION	non-polymer		158.9	2	Chemie (TB)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	23168.4
Non-Polymers*	Number of molecules	2
	Total formula weight	317.9
All*	Total formula weight	23486.3

*Water molecules are not included.