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2RSE

NMR structure of FKBP12-mTOR FRB domain-rapamycin complex structure determined based on PCS

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Peptidyl-prolyl cis-trans isomerase FKBP1Apolymer10711836.51UniProt (P62942)
Pfam (PF00254)
Homo sapiens (human)PPIase FKBP1A, 12 kDa FK506-binding protein, 12 kDa FKBP, FKBP-12, FK506-binding protein 1A, FKBP-1A, Immunophilin FKBP12, Rotamase
2B
(B)
Serine/threonine-protein kinase mTORpolymer9411331.91UniProt (P42345)
Pfam (PF08771)
Homo sapiens (human)FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, mTOR, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapamycin target protein 1
3C, D
(A)
TERBIUM(III) IONnon-polymer158.92Chemie (TB)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight23168.4
Non-Polymers*Number of molecules2
Total formula weight317.9
All*Total formula weight23486.3
*Water molecules are not included.

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PDB entries from 2026-02-04

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