2RSE
NMR structure of FKBP12-mTOR FRB domain-rapamycin complex structure determined based on PCS
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Peptidyl-prolyl cis-trans isomerase FKBP1A | polymer | 107 | 11836.5 | 1 | UniProt (P62942) Pfam (PF00254) In PDB | Homo sapiens (human) | PPIase FKBP1A, 12 kDa FK506-binding protein, 12 kDa FKBP, FKBP-12, FK506-binding protein 1A, FKBP-1A, Immunophilin FKBP12, Rotamase |
2 | B | Serine/threonine-protein kinase mTOR | polymer | 94 | 11331.9 | 1 | UniProt (P42345) Pfam (PF08771) In PDB | Homo sapiens (human) | FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, mTOR, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapamycin target protein 1 |
3 | A | TERBIUM(III) ION | non-polymer | 158.9 | 2 | Chemie (TB) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 23168.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 317.9 | |
All* | Total formula weight | 23486.3 |