2RN5

Humal Insulin Mutant B31Lys-B32Arg

Summary for 2RN5
NMR InformationBMRB: 11016
DescriptorInsulin (2 entities in total)
Functional Keywordshuman insulin mutant, 35% cd3cn, monomer, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, glucose metabolism, hormone, pharmaceutical, secreted
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P01308 P01308
Total number of polymer chains2
Total formula weight6104.02
Authors
Bocian, W.,Kozerski, L. (deposition date: 2007-12-06, release date: 2008-10-28, Last modification date: 2011-07-13)
Primary citationBednarek, E.,Bocian, W.,Bogiel, M.,Borowicz, P.,Kozerski, L.,Sitkowski, J.,Tarnowska, A.
NMR structure of biosynthetic engineered human insulin monomer B31(Lys)-B32(Arg) in water/acetonitrile solution. Comparison with the solution structure of native human insulin monomer
Biopolymers, 89:820-830, 2008
PubMed: 18491415
DOI: 110.1002/bip.21018
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation
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PDB entries from 2021-06-23