2R0D

Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor

Summary for 2R0D

• Entry DOI: 10.2210/pdb2r0d/pdb
• Related: 2r09
• Descriptor: Cytohesin-3, SULFATE ION, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, ... (5 entities in total)
• Functional Keywords: grp1, general receptor for phosphoinositides, arf gtpase, exchange factor, pip3, 3-phosphoinositide, guanine-nucleotide releasing factor, signaling protein
• Biological source: Mus musculus (house mouse)
• Cellular location: Cell membrane (By similarity): O08967
• Total number of polymer chains: 2
• Total formula weight: 82484.64

Authors

DiNitto, J.P.,Delprato, A.,Gabe Lee, M.T.,Cronin, T.C.,Huang, S.,Guilherme, A.,Czech, M.P.,Lambright, D.G. (deposition date: 2007-08-18, release date: 2007-12-04, Last modification date: 2024-02-21)

• Primary citation: DiNitto, J.P.,Delprato, A.,Gabe Lee, M.T.,Cronin, T.C.,Huang, S.,Guilherme, A.,Czech, M.P.,Lambright, D.G.; Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange Factors.; Mol.Cell, 28:569-583, 2007; PubMed: 18042453; DOI: 10.1016/j.molcel.2007.09.017

Experimental method

X-RAY DIFFRACTION (2.04 Å)