2QS2
Crystal structure of the GluR5 ligand binding core dimer in complex with UBP318 at 1.80 Angstroms resolution
Summary for 2QS2
Entry DOI | 10.2210/pdb2qs2/pdb |
Related | 1TXF 2F34 2F35 2F36 2QS1 2QS3 2QS4 |
Descriptor | Glutamate receptor, ionotropic kainate 1, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... (5 entities in total) |
Functional Keywords | membrane protein, cell junction, glycoprotein, ion transport, ionic channel, phosphorylation, postsynaptic cell membrane, receptor, rna editing, synapse, transmembrane, transport |
Biological source | Rattus norvegicus (rat) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P22756 |
Total number of polymer chains | 2 |
Total formula weight | 59806.96 |
Authors | Alushin, G.M.,Jane, D.E.,Mayer, M.L. (deposition date: 2007-07-30, release date: 2008-08-05, Last modification date: 2023-08-30) |
Primary citation | Alushin, G.M.,Jane, D.,Mayer, M.L. Binding site and ligand flexibility revealed by high resolution crystal structures of GluK1 competitive antagonists. Neuropharmacology, 60:126-134, 2011 Cited by PubMed: 20558186DOI: 10.1016/j.neuropharm.2010.06.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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