2PNO
Crystal structure of human leukotriene C4 synthase
Summary for 2PNO
Entry DOI | 10.2210/pdb2pno/pdb |
Descriptor | Leukotriene C4 synthase, GLUTATHIONE, DODECYL-BETA-D-MALTOSIDE (3 entities in total) |
Functional Keywords | membrane protein, helix bundle, homo trimer, mgst, mapeg, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus outer membrane; Multi-pass membrane protein: Q16873 |
Total number of polymer chains | 12 |
Total formula weight | 241731.40 |
Authors | Ago, H.,Kanaoka, Y.,Irikura, D.,Lam, B.K.,Shimamura, T.,Austen, K.F.,Miyano, M. (deposition date: 2007-04-24, release date: 2007-08-07, Last modification date: 2024-03-13) |
Primary citation | Ago, H.,Kanaoka, Y.,Irikura, D.,Lam, B.K.,Shimamura, T.,Austen, K.F.,Miyano, M. Crystal structure of a human membrane protein involved in cysteinyl leukotriene biosynthesis Nature, 448:609-612, 2007 Cited by PubMed: 17632548DOI: 10.1038/nature05936 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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