2PGB
Inhibitor-free human thrombin mutant C191A-C220A
Summary for 2PGB
Entry DOI | 10.2210/pdb2pgb/pdb |
Related | 1SHH 2PGQ |
Descriptor | Prothrombin, 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (5 entities in total) |
Functional Keywords | serine protease, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 34225.96 |
Authors | Bush-Pelc, L.A.,Marino, F.,Chen, Z.,Pineda, A.O.,Mathews, F.S.,Di Cera, E. (deposition date: 2007-04-09, release date: 2007-07-17, Last modification date: 2023-08-30) |
Primary citation | Bush-Pelc, L.A.,Marino, F.,Chen, Z.,Pineda, A.O.,Mathews, F.S.,Di Cera, E. Important role of the cys-191 cys-220 disulfide bond in thrombin function and allostery J.Biol.Chem., 282:27165-27170, 2007 Cited by PubMed: 17636263DOI: 10.1074/jbc.M703202200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.54 Å) |
Structure validation
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