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2PGB

Inhibitor-free human thrombin mutant C191A-C220A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AProthrombinpolymer364096.51UniProt (P00734)
Pfam (PF09396)
In PDB
Homo sapiens (human)Coagulation factor II
2BProthrombinpolymer25929716.11UniProt (P00734)
Pfam (PF00089)
In PDB
Homo sapiens (human)Coagulation factor II
3B2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
4BSULFATE IONnon-polymer96.12Chemie (SO4)
5waterwater18.0282Chemie (HOH)
Sequence modifications
B: 16 - 247 (UniProt: P00734)
PDBExternal DatabaseDetails
Ala 191Cys 564engineered mutation
Ala 220Cys 594engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight33812.6
Non-Polymers*Number of molecules3
Total formula weight413.3
All*Total formula weight34226.0
*Water molecules are not included.

221051

PDB entries from 2024-06-12

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