2PED

Crystallographic model of 9-cis-rhodopsin

Summary for 2PED

• Entry DOI: 10.2210/pdb2ped/pdb
• Related: 1U19 2G87
• Descriptor: Rhodopsin, HEPTANE-1,2,3-TRIOL, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• Functional Keywords: rhodopsin, g protein-coupled receptor, visual pigment, signaling protein
• Biological source: Bos taurus (cattle)
• Cellular location: Membrane; Multi-pass membrane protein: P02699
• Total number of polymer chains: 2
• Total formula weight: 85393.66

Authors

Nakamichi, H.,Okada, T. (deposition date: 2007-04-02, release date: 2007-10-30, Last modification date: 2024-10-30)

Primary citation

Nakamichi, H.,Buss, V.,Okada, T.
Photoisomerization mechanism of rhodopsin and 9-cis-rhodopsin revealed by x-ray crystallography
Biophys.J., 92:L106-L108, 2007

PubMed Abstract: The primary photochemical process of the visual function has been investigated using the three crystallographic models, 11-cis-rhodopsin, all-trans-bathorhodopsin, and the artificial isomeric 9-cis-rhodopsin. Detailed examination of the atomic displacements and dihedral angle changes of the retinal chromophore involved in the interconversion among these isomers suggests the mechanism of isomerization efficiency.

PubMed: 17449675
DOI: 10.1529/biophysj.107.108225

Experimental method

X-RAY DIFFRACTION (2.95 Å)