2P66
Human DNA Polymerase beta complexed with tetrahydrofuran (abasic site) containing DNA
Summary for 2P66
Entry DOI | 10.2210/pdb2p66/pdb |
Descriptor | DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3'), DNA (5'-D(P*(3DR)P*GP*TP*CP*GP*G)-3'), ... (7 entities in total) |
Functional Keywords | dna repair, base excision repair, drp lyase, transferase, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P06746 |
Total number of polymer chains | 4 |
Total formula weight | 48325.09 |
Authors | Prasad, R.,Batra, V.K.,Yang, X.-P.,Krahn, J.M.,Pedersen, L.C.,Beard, W.A.,Wilson, S.H. (deposition date: 2007-03-16, release date: 2007-04-10, Last modification date: 2023-08-30) |
Primary citation | Prasad, R.,Batra, V.K.,Yang, X.-P.,Krahn, J.M.,Pedersen, L.C.,Beard, W.A.,Wilson, S.H. Structural insight into the DNA Polymerase beta deoxyribose phosphate lyase mechanism DNA REPAIR, 4:1347-1357, 2005 Cited by PubMed: 16172026DOI: 10.1016/j.dnarep.2005.08.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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