2NTD

Human fibroblast growth factor-1 (140 amino acid form) with Cys117Val/Pro134Cys mutations

Summary for 2NTD

• Entry DOI: 10.2210/pdb2ntd/pdb
• Related: 1JY0
• Descriptor: Acidic fibroblast growth factor 1, FORMIC ACID (3 entities in total)
• Functional Keywords: beta-trefoil, hormone-growth factor complex, hormone/growth factor
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P05230
• Total number of polymer chains: 4
• Total formula weight: 67261.33

Authors

Dubey, V.K.,Blaber, M. (deposition date: 2006-11-07, release date: 2007-07-24, Last modification date: 2023-08-30)

• Primary citation: Dubey, V.K.,Lee, J.,Somasundaram, T.,Blaber, S.,Blaber, M.; Spackling the Crack: Stabilizing Human Fibroblast Growth Factor-1 by Targeting the N and C terminus beta-Strand Interactions; J.Mol.Biol., 371:256-268, 2007; PubMed: 17570396; DOI: 10.1016/j.jmb.2007.05.065

Experimental method

X-RAY DIFFRACTION (2.52 Å)