2NOY
Crystal structure of transthyretin mutant I84S at PH 7.5
Summary for 2NOY
Entry DOI | 10.2210/pdb2noy/pdb |
Related | 2G3X 2G3Z 2G4E 2G4G |
Descriptor | Transthyretin (2 entities in total) |
Functional Keywords | ttr, amyloid fibrils, point mutation, transport protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 27502.56 |
Authors | Pasquato, N.,Berni, R.,Folli, C.,Alfieri, B.,Cendron, L.,Zanotti, G. (deposition date: 2006-10-26, release date: 2007-01-16, Last modification date: 2023-10-25) |
Primary citation | Pasquato, N.,Berni, R.,Folli, C.,Alfieri, B.,Cendron, L.,Zanotti, G. Acidic pH-induced conformational changes in amyloidogenic mutant transthyretin J.Mol.Biol., 366:711-719, 2007 Cited by PubMed: 17196219DOI: 10.1016/j.jmb.2006.11.076 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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