2N3K
Human Brd4 ET domain in complex with MLV Integrase C-term
Summary for 2N3K
Entry DOI | 10.2210/pdb2n3k/pdb |
NMR Information | BMRB: 25649 |
Descriptor | Bromodomain-containing protein 4, MLV integrase (2 entities in total) |
Functional Keywords | brd4 et, mlv integrase, protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: O60885 |
Total number of polymer chains | 2 |
Total formula weight | 12150.96 |
Authors | Crowe, B.L.,Foster, M.P. (deposition date: 2015-06-03, release date: 2016-03-02, Last modification date: 2024-05-15) |
Primary citation | Crowe, B.L.,Larue, R.C.,Yuan, C.,Hess, S.,Kvaratskhelia, M.,Foster, M.P. Structure of the Brd4 ET domain bound to a C-terminal motif from gamma-retroviral integrases reveals a conserved mechanism of interaction. Proc.Natl.Acad.Sci.USA, 113:2086-2091, 2016 Cited by PubMed: 26858406DOI: 10.1073/pnas.1516813113 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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