2N0Y
NMR structure of the complex between the C-terminal domain of the Rift Valley fever virus protein NSs and the PH domain of the Tfb1 subunit of TFIIH
Summary for 2N0Y
| Entry DOI | 10.2210/pdb2n0y/pdb |
| Related | 1y5o 2lox 2m14 |
| NMR Information | BMRB: 25540 |
| Descriptor | RNA polymerase II transcription factor B subunit 1, Non-structural protein NS-S (2 entities in total) |
| Functional Keywords | transcription, virulence, viral protein-transcription complex, drug target, virus-host interface, transcription-viral protein complex, transcription/viral protein |
| Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
| Cellular location | Nucleus: P32776 |
| Total number of polymer chains | 2 |
| Total formula weight | 15470.19 |
| Authors | Cyr, N.,de la Fuente, C.,Lecoq, L.,Guendel, I.,Chabot, P.R.,Kehn-Hall, K.,Omichinski, J.G. (deposition date: 2015-03-18, release date: 2015-04-22, Last modification date: 2023-06-14) |
| Primary citation | Cyr, N.,de la Fuente, C.,Lecoq, L.,Guendel, I.,Chabot, P.R.,Kehn-Hall, K.,Omichinski, J.G. A Omega XaV motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulence. Proc.Natl.Acad.Sci.USA, 112:6021-6026, 2015 Cited by PubMed: 25918396DOI: 10.1073/pnas.1503688112 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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