2MZP
Structure and dynamics of the acidosis-resistant a162H mutant of the switch region of troponin I bound to the regulatory domain of troponin C
Summary for 2MZP
| Entry DOI | 10.2210/pdb2mzp/pdb |
| NMR Information | BMRB: 25495 |
| Descriptor | Troponin C, slow skeletal and cardiac muscles, Troponin I, cardiac muscle, CALCIUM ION (3 entities in total) |
| Functional Keywords | contraction regulation, contraction enhancenment, troponin, acidosis, ca2+ binding, contractile protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 13183.02 |
| Authors | Pineda Sanabria, S.E.,Robertson, I.M.,Sykes, B.D. (deposition date: 2015-02-20, release date: 2015-06-03, Last modification date: 2023-06-14) |
| Primary citation | Pineda-Sanabria, S.E.,Robertson, I.M.,Sykes, B.D. Structure and Dynamics of the Acidosis-Resistant A162H Mutant of the Switch Region of Troponin I Bound to the Regulatory Domain of Troponin C. Biochemistry, 54:3583-3593, 2015 Cited by PubMed: 25996354DOI: 10.1021/acs.biochem.5b00178 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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