2MZP
Structure and dynamics of the acidosis-resistant a162H mutant of the switch region of troponin I bound to the regulatory domain of troponin C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | C | Troponin C, slow skeletal and cardiac muscles | polymer | 89 | 10070.3 | 1 | UniProt (P63316) Pfam (PF13833) In PDB | Homo sapiens (human) | TN-C |
| 2 | I | Troponin I, cardiac muscle | polymer | 27 | 3072.6 | 1 | UniProt (P19429) In PDB | Homo sapiens | Cardiac troponin I |
| 3 | C | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) |
Sequence modifications
I: 144 - 170 (UniProt: P19429)
| PDB | External Database | Details |
|---|---|---|
| His 162 | Ala 163 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 13142.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 40.1 | |
| All* | Total formula weight | 13183.0 |
