2MVC

Solution structure of human insulin at pH 1.9

Summary for 2MVC
Related2HIU 2MVD
NMR InformationBMRB: 25260
DescriptorInsulin A chain, Insulin B chain (2 entities in total)
Functional Keywordsinsulin, hormone
Biological sourceHomo sapiens (Human)
More
Cellular locationSecreted: P01308 P01308
Total number of polymer chains2
Total formula weight5817.65
Authors
Hexnerova, R.,Krizkova, K.,Maletinska, L.,Jiracek, J.,Brzozowski, A.M.,Zakova, L.,Veverka, V. (deposition date: 2014-10-02, release date: 2014-12-10, Last modification date: 2016-06-01)
Primary citationBrzozowski, A.M.,Hexnerova, R.,Jiracek, J.,Krizkova, K.,Maletinska, L.,Veverka, V.,Zakova, L.
Structural and Functional Study of the GlnB22-Insulin Mutant Responsible for Maturity-Onset Diabetes of the Young.
Plos One, 9:e112883-e112883, 2014
PubMed: 25423173
DOI: 110.1371/journal.pone.0112883
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation
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PDB entries from 2021-06-23