2MUB
Solution structure of the analgesic sea anemone peptide APETx2
Summary for 2MUB
Entry DOI | 10.2210/pdb2mub/pdb |
Related | 1WXN |
NMR Information | BMRB: 25205 |
Descriptor | Toxin APETx2 (1 entity in total) |
Functional Keywords | disulfide-rich toxin, defensin fold, toxin, asic3 blocker |
Biological source | Anthopleura elegantissima (Sea anemone) |
Cellular location | Secreted : P61542 |
Total number of polymer chains | 1 |
Total formula weight | 4571.12 |
Authors | Mobli, M.,King, G.F.,Rosengren, K.J.,Jensen, J.E. (deposition date: 2014-09-07, release date: 2014-12-24, Last modification date: 2023-06-14) |
Primary citation | Jensen, J.E.,Cristofori-Armstrong, B.,Anangi, R.,Rosengren, K.J.,Lau, C.H.,Mobli, M.,Brust, A.,Alewood, P.F.,King, G.F.,Rash, L.D. Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores. J.Med.Chem., 57:9195-9203, 2014 Cited by PubMed: 25337890DOI: 10.1021/jm501400p PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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