2MT7
Solution structure of spider-venom peptide Hs1a
Summary for 2MT7
Entry DOI | 10.2210/pdb2mt7/pdb |
NMR Information | BMRB: 25151 |
Descriptor | Hs1a (1 entity in total) |
Functional Keywords | spider-venom peptide, inhibitor cystine knot, nav1.7, nav channel inhibitor, ion channel modulator, toxin |
Biological source | Hysterocrates |
Total number of polymer chains | 1 |
Total formula weight | 3866.54 |
Authors | Klint, J.K.,King, G.F.,Mobli, M. (deposition date: 2014-08-14, release date: 2015-08-19, Last modification date: 2023-06-14) |
Primary citation | Klint, J.K.,Castro, J.,Vetter, I.,Er, S.Y.,Cardoso, F.,Liu, Y.,Hagan, R.,Neff, R.,Minassian, N.,Huang, J.X.,Cooper, M.A.,Wickenden, A.,Mobli, M.,Jin, L.,Nicolazzo, J.A.,Lewis, R.J.,Bosmans, F.,Brierley, S.M.,King, G.F. Nav1.7 inhibitors normalise mechanical responses in chronic visceral hypersensitivity To be Published, |
Experimental method | SOLUTION NMR |
Structure validation
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