2MPQ

Solution structure of the sodium channel toxin Hd1a

Summary for 2MPQ

• Entry DOI: 10.2210/pdb2mpq/pdb
• NMR Information: BMRB: 19998
• Descriptor: Hd1a (1 entity in total)
• Functional Keywords: spider toxin, disulfide-rich peptide, sodium channel, knottin, inhibitor cystine knot, toxin
• Biological source: Haplopelma doriae
• Total number of polymer chains: 1
• Total formula weight: 3891.48

Authors

Klint, J.K.,Mobli, M.,King, G.F. (deposition date: 2014-06-01, release date: 2015-03-25, Last modification date: 2023-06-14)

• Primary citation: Klint, J.K.,Smith, J.J.,Vetter, I.,Rupasinghe, D.B.,Er, S.Y.,Senff, S.,Herzig, V.,Mobli, M.,Lewis, R.J.,Bosmans, F.,King, G.F.; Seven novel modulators of the analgesic target NaV 1.7 uncovered using a high-throughput venom-based discovery approach.; Br.J.Pharmacol., 172:2445-2458, 2015; PubMed: 25754331; DOI: 10.1111/bph.13081

Experimental method

SOLUTION NMR