2MPC
Solution structure of the pyrin domain of human Pyrin
Summary for 2MPC
Entry DOI | 10.2210/pdb2mpc/pdb |
NMR Information | BMRB: 19875 |
Descriptor | Pyrin (1 entity in total) |
Functional Keywords | pyrin domain, death domain, inflammation, cs-rosetta, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Cytoplasm, cytoskeleton. Isoform 2: Nucleus: O15553 |
Total number of polymer chains | 1 |
Total formula weight | 11826.58 |
Authors | Soh, S.L.,Smith, S.J.,Hill, J.M. (deposition date: 2014-05-15, release date: 2014-07-16, Last modification date: 2024-05-15) |
Primary citation | Vajjhala, P.R.,Kaiser, S.,Smith, S.J.,Ong, Q.R.,Soh, S.L.,Stacey, K.J.,Hill, J.M. Identification of multifaceted binding modes for pyrin and ASC pyrin domains gives insights into pyrin inflammasome assembly. J.Biol.Chem., 289:23504-23519, 2014 Cited by PubMed: 25006247DOI: 10.1074/jbc.M114.553305 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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