2MML
T47 phosphorylation of the Mengovirus Leader Protein: NMR Studies of the Phosphorylation of the Mengovirus Leader Protein Reveal Stabilization of Intermolecular Domain Interactions
Summary for 2MML
| Entry DOI | 10.2210/pdb2mml/pdb |
| Related | 2MMG 2MMH 2MMI 2MMK |
| NMR Information | BMRB: 19858 |
| Descriptor | Leader protein, ZINC ION (2 entities in total) |
| Functional Keywords | animal viruses, positive-strand rna viruses, cardioviruses, leader, protein phosphorylation, casein kinase 2, viral protein |
| Biological source | Mengo virus |
| Cellular location | Protein 2A: Host nucleus . Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3B: Virion . Protease 3C: Host cytoplasm . RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : P12296 |
| Total number of polymer chains | 1 |
| Total formula weight | 8407.43 |
| Authors | Bacot-Davis, V.R.,Porter, F.W.,Palmenberg, A.C. (deposition date: 2014-03-15, release date: 2014-10-15, Last modification date: 2023-06-14) |
| Primary citation | Bacot-Davis, V.R.,Ciomperlik, J.J.,Basta, H.A.,Cornilescu, C.C.,Palmenberg, A.C. Solution structures of Mengovirus Leader protein, its phosphorylated derivatives, and in complex with nuclear transport regulatory protein, RanGTPase. Proc.Natl.Acad.Sci.USA, 111:15792-15797, 2014 Cited by PubMed: 25331866DOI: 10.1073/pnas.1411098111 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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