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2MMI

Mengovirus Leader: Structural Characterization of the Mengovirus Leader Protein Bound to Ran GTPase by Nuclear Magnetic Resonance

Summary for 2MMI
Entry DOI10.2210/pdb2mmi/pdb
Related2MMG 2MMH 2MMK 2MML
NMR InformationBMRB: 19855
DescriptorLeader protein, ZINC ION (2 entities in total)
Functional Keywordsanimal viruses, positive-strand rna viruses, cardioviruses, leader, nucleocytoplasmic transport, viral protein
Biological sourceMengo virus
Cellular locationProtein 2A: Host nucleus . Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3B: Virion . Protease 3C: Host cytoplasm . RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : P12296
Total number of polymer chains1
Total formula weight8327.45
Authors
Bacot-Davis, V.R.,Cornilescu, C.C.,Markley, J.L.,Palmenberg, A.C. (deposition date: 2014-03-15, release date: 2014-10-15, Last modification date: 2023-06-14)
Primary citationBacot-Davis, V.R.,Ciomperlik, J.J.,Basta, H.A.,Cornilescu, C.C.,Palmenberg, A.C.
Solution structures of Mengovirus Leader protein, its phosphorylated derivatives, and in complex with nuclear transport regulatory protein, RanGTPase.
Proc.Natl.Acad.Sci.USA, 111:15792-15797, 2014
Cited by
PubMed: 25331866
DOI: 10.1073/pnas.1411098111
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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