2MG1

NMR assignment and structure of a peptide derived from the trans-membrane region of HIV-1 gp41 in the presence of hexafluoroisopropanol

Summary for 2MG1

• Entry DOI: 10.2210/pdb2mg1/pdb
• Related: 2MG1 2MG2 2MG3
• NMR Information: BMRB: 19581
• Descriptor: Transmembrane protein gp41 (1 entity in total)
• Functional Keywords: hiv-1 gp41 protein, transmembrane domain, viral entry, membrane fusion glycoprotein, viral protein
• Biological source: Human immunodeficiency virus 1 (HIV-1)
• Cellular location: Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P04578
• Total number of polymer chains: 1
• Total formula weight: 3006.93

Authors

Serrano, S.,Apellaniz, B.,Huarte, N.L.,Nieva, J.L.,Jimenez, M.A. (deposition date: 2013-10-24, release date: 2015-03-25, Last modification date: 2023-06-14)

• Primary citation: Apellaniz, B.,Rujas, E.,Serrano, S.,Morante, K.,Tsumoto, K.,Caaveiro, J.M.,Jimenez, M.A.,Nieva, J.L.; The Atomic Structure of the HIV-1 gp41 Transmembrane Domain and Its Connection to the Immunogenic Membrane-proximal External Region.; J.Biol.Chem., 290:12999-13015, 2015; PubMed: 25787074; DOI: 10.1074/jbc.M115.644351

Experimental method

SOLUTION NMR