2LJC

Structure of the influenza AM2-BM2 chimeric channel bound to rimantadine

Summary for 2LJC

• Entry DOI: 10.2210/pdb2ljc/pdb
• Related: 2KIX 2KWX 2RLF 2ljb
• NMR Information: BMRB: 17929
• Descriptor: M2 protein, BM2 protein chimera, RIMANTADINE (2 entities in total)
• Functional Keywords: m2 channel, rimantadine binding, drug complex, transport protein, transport protein-inhibitor complex, transport protein/inhibitor
• Biological source: Influenza A virus, Influenza B virus
• Total number of polymer chains: 4
• Total formula weight: 15400.79

Authors

Pielak, R.M.,Oxenoid, K.,Chou, J.J. (deposition date: 2011-09-10, release date: 2011-11-16, Last modification date: 2012-03-21)

• Primary citation: Pielak, R.M.,Oxenoid, K.,Chou, J.J.; Structural investigation of rimantadine inhibition of the AM2-BM2 chimera channel of influenza viruses.; Structure, 19:1655-1663, 2011; PubMed: 22078564; DOI: 10.1016/j.str.2011.09.003

Experimental method

SOLUTION NMR