2LGB

Modified A22Gly-B31Arg Human Insulin

Summary for 2LGB
NMR InformationBMRB: 17803
DescriptorInsulin A chain, Insulin B chain (2 entities in total)
Functional Keywordshormone
Biological sourceHomo sapiens (human)
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Cellular locationSecreted: P01308 P01308
Total number of polymer chains2
Total formula weight6031.90
Authors
Bocian, W.,Kozerski, L. (deposition date: 2011-07-25, release date: 2012-04-11, Last modification date: 2012-07-04)
Primary citationBednarek, E.,Bocian, W.,Bogiel, M.,Borowicz, P.,Glabski, T.,Jaworska, B.,Kozerski, L.,Mikolajczyk, J.,Sitkowski, J.,Stadnik, D.,Surmacz, W.
Recombinant A22(G)-B31 (R)-human insulin. A22 addition introduces conformational mobility in B chain C-terminus.
J.Biomol.Nmr, 52:365-370, 2012
PubMed: 22350952
DOI: 110.1007/s10858-012-9612-y
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation
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PDB entries from 2021-06-23