2KXQ
Solution Structure of Smurf2 WW2 and WW3 bound to Smad7 PY motif containing peptide
Summary for 2KXQ
| Entry DOI | 10.2210/pdb2kxq/pdb |
| NMR Information | BMRB: 16923 |
| Descriptor | E3 ubiquitin-protein ligase SMURF2, Smad7 PY motif containing peptide (2 entities in total) |
| Functional Keywords | ww, py motif, smurf2, tgf-beta, modular binding, protein binding |
| Biological source | Homo sapiens (human) More |
| Cellular location | Nucleus: Q9HAU4 |
| Total number of polymer chains | 2 |
| Total formula weight | 12304.42 |
| Authors | Chong, A.,Lin, H.,Wrana, J.,Forman-Kay, J.D. (deposition date: 2010-05-11, release date: 2010-10-13, Last modification date: 2012-06-20) |
| Primary citation | Chong, P.A.,Lin, H.,Wrana, J.L.,Forman-Kay, J.D. Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity. Proc.Natl.Acad.Sci.USA, 107:18404-18409, 2010 Cited by PubMed: 20937913DOI: 10.1073/pnas.1003023107 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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