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2KXQ

Solution Structure of Smurf2 WW2 and WW3 bound to Smad7 PY motif containing peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
E3 ubiquitin-protein ligase SMURF2polymer9010114.01UniProt (Q9HAU4)
Pfam (PF00397)
Homo sapiens (human)hSMURF2, SMAD ubiquitination regulatory factor 2, SMAD-specific E3 ubiquitin-protein ligase 2
2B
(B)
Smad7 PY motif containing peptidepolymer202190.41UniProt (by SIFTS) (O15105)Homo sapiens (human)
Sequence modifications
A: 250 - 333 (UniProt: Q9HAU4)
PDBExternal DatabaseDetails
Gly 244-expression tag
Pro 245-expression tag
Leu 246-expression tag
Gly 247-expression tag
Gly 248-expression tag
Ser 249-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight12304.4
All*Total formula weight12304.4
*Water molecules are not included.

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PDB entries from 2025-06-25

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