2KTD

Solution structure of mouse lipocalin-type prostaglandin D synthase / substrate analog (U-46619) complex

Summary for 2KTD

• Entry DOI: 10.2210/pdb2ktd/pdb
• Descriptor: Prostaglandin-H2 D-isomerase, (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid (2 entities in total)
• Functional Keywords: lipocalin-type prostaglandin d synthase, l-pgds, prostaglandin h2, prostaglandin d2, u-46619, lipocalin, disulfide bond, endoplasmic reticulum, fatty acid biosynthesis, glycoprotein, golgi apparatus, isomerase, lipid synthesis, nucleus, prostaglandin biosynthesis, pyrrolidone carboxylic acid, secreted, transport
• Biological source: Mus musculus (mouse)
• Cellular location: Rough endoplasmic reticulum (By similarity): O09114
• Total number of polymer chains: 1
• Total formula weight: 18936.29

Authors

Shimamoto, S.,Maruo, H.,Yoshida, T.,Kato, N.,Ohkubo, T. (deposition date: 2010-01-27, release date: 2011-02-02, Last modification date: 2011-07-13)

• Primary citation: Shimamoto, S.,Maruo, H.,Yoshida, T.,Inui, T.,Miyamoto, Y.,Kobayashi, Y.,Tsurumura, T.,Aritake, K.,Urade, Y.,Ohkubo, T.; Solution Structure of Lipocalin-type Prostaglandin D synthase / Substrate analog complex reveals Open-Closed Conformational Change required for Substrate Recognition; To be Published,

Experimental method

SOLUTION NMR